Tehran University of Medical Sciences Current Journal of Neurology 2717-011X 14 1 2015 03 15 22 28 Zeinab Taheri Department of Neurology, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Hosein Harirchian Department of Neurology, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran. Hosein Ghanaati Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Alireza Khoshnevisan Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Payman Salamati Department of Community Medicine, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. Mojtaba Miri Department of Neurosurgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Kavous Firouznia Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Mina Saeednejad Department of Radiology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran. Madjid Shakiba Department of Radiology, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. Vafa Rahimi-Movaghar Department of Neurosurgery, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 14 Background: Management of intracranial aneurysms has made debates about the best treatment modality in recent years. The aim of this study was to compare the interventional outcomes between two groups of patients, one treated with endovascular coiling and the other treated with surgical clipping. Methods: This prospective study included 48 patients with intracranial aneurysms who underwent endovascular coiling (27 patients) or surgical clipping (21 patients) from July 2011 to August 2013. A neurologist examined patients in admission and followed them by phone call 1-year after intervention. Results: Mean modified Rankin Scale (MRS) score at the  time  of  admission  in  endovascular  group  was 2.86 ± 0.974 whereas it was 3.81 ± 1.078 in surgical clipping group (P  = 0.0040). Focal neurologic signs were higher in clipping during procedures (P = 0.0310). Of 37 patients who followed up for a year, 19 were in endovascular group and 18 in surgical clipping group. At 1 year follow-up, MRS improvement was statistic lly significant in  coiling group (P =  0.0090), but not  in clipping group (P = 0.8750). Mean difference of MRS score at the time of admission and at one year later, was   0.947   ±   1.224   in   endo vascular   group   and 0.111 ± 2.083 in surgical group (P = 0.3000). Conclusion:  There  was  no  statistically  significant difference at 1 year outcome between two groups. We recommend further  interventional studies  with  larger sample sizes for better evaluation of the modalities. https://ijnl.tums.ac.ir/index.php/ijnl/article/view/577 https://ijnl.tums.ac.ir/index.php/ijnl/article/download/577/225