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<Articles JournalTitle="Current Journal of Neurology">
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Current Journal of Neurology</JournalTitle>
      <Issn>2717-011X</Issn>
      <Volume>13</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2014</Year>
        <Month>09</Month>
        <Day>15</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Seizures and movement disorders induced by hyperglycemia without ketosis in elderly.</title>
    <FirstPage>172</FirstPage>
    <LastPage>176</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Samia</FirstName>
        <LastName>Younes</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Yousra</FirstName>
        <LastName>Cherif</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Mouna</FirstName>
        <LastName>Aissi</LastName>
        <affiliation locale="en_US">Department of Neurology, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Wafa</FirstName>
        <LastName>Alaya</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Olfa</FirstName>
        <LastName>Berriche</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Amel</FirstName>
        <LastName>Boughammoura</LastName>
        <affiliation locale="en_US">Department of Neurology, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Mahbouba</FirstName>
        <LastName>Frih-Ayed</LastName>
        <affiliation locale="en_US">Department of Neurology, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Baha</FirstName>
        <LastName>Zantour</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
      <Author>
        <FirstName>Mohamed</FirstName>
        <LastName>Habib Sfar</LastName>
        <affiliation locale="en_US">Department of Endocrinology and Internal Medicine, School of Medicine, University of Monastir, Al Munast&#xEE;r, Tunisia.</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2015</Year>
        <Month>10</Month>
        <Day>14</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Background: Non-ketotic hyperglycemia (NKHG) may increase the probability of seizures and movement disorders. Methods: We describe&#xA0; a series of 14 elders admitted for seizures and movement disorders linked to NKHG.
Results: Twelve&#xA0; patients&#xA0; developed motor&#xA0; seizures&#xA0; and two others movement disorders. Glucose levels varied 9.28 to 32 mmol/l, while osmolarity values varied from 302.28 to 328&#xA0; mosmol/l. All patients&#xA0; responded&#xA0; well&#xA0; to&#xA0; insulin therapy and four of them needed anti-epileptic drugs.
Conclusion:&#xA0; Seizures or&#xA0; movement disorders&#xA0; in elderly with&#xA0;&#xA0; NKHG could be&#xA0; misdiagnosed as neurological diseases. Blood&#xA0; glucose must&#xA0; be audited&#xA0; whenever patients with seizures&#xA0;&#xA0; or&#xA0;&#xA0; movement disorders&#xA0; are encountered, as the condition&#xA0; may quickly resolve when NKHG is controlled.
Introduction: Seizures and movement disorders related to non- ketotic hyperglycemia (NKHG) have been reported with increasing frequency since the first case documented in 1965.1,2 The clinical spectr m of this syndrome is various with a severe course in elderly. It develops more&#xA0; quickly&#xA0;&#xA0; than other disorders of diabetes&#xA0; mellitus&#xA0; with&#xA0; hyperglycemia,&#xA0; but&#xA0; usually without&#xA0; evidence&#xA0; of&#xA0; ketosis.2,3 Since&#xA0; the&#xA0; syndrome often ensues during the course of any illness and yet has&#xA0; not&#xA0; been&#xA0; reported&#xA0; in&#xA0; diverse&#xA0; medical&#xA0; fields, doctors must become familiar with this preventable condition, especially in elders. Thus, only the prompt institution of appropriate&#xA0; insulin&#xA0; therapy&#xA0; will improve prognosis and hasten recovery.2,3</abstract>
    <web_url>https://ijnl.tums.ac.ir/index.php/ijnl/article/view/600</web_url>
    <pdf_url>https://ijnl.tums.ac.ir/index.php/ijnl/article/download/600/202</pdf_url>
  </Article>
</Articles>
