Tehran University of Medical Sciences Current Journal of Neurology 2717-011X 13 2 2014 06 15 77 82 Fariba Yadegari Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Mojtaba Azimian Department of Clinical Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Mahdi Rahgozar Department of Statistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Babak Shekarchi Department of Radiology, School of Medicine, AJA University, Tehran, Iran. 2015 10 14 Background: As both oral and verbal apraxia are related  to vocal orofacial musculature, this study aimed at identifying brain regions impaired in cases with oral and verbal apraxia. Methods:  In  this non-experimental  study,  46  left  brain damaged subjects (17 females)  aged  23–84  years,  were examined  by oral and  verbal apraxia tasks.  Impaired  and spared Broca’s area, insula, and middle frontal gyrus in the left hemisphere  were  checked  from magnetic  resonance imaging    and  computed   tomography  scans  utilizing Talairach Atlas. Data were analyzed using chi-square test. Results: Insula was significantly impaired  in both  forms of oral   and verbal apraxia  and  different   severities   and prominent forms of both apraxias (P < 0.05). Broca’s area was slightly less involved than insula in two forms of apraxia. Conclusion: As the damage  of insula was more prominent in both  forms  of apraxias,  it seems  that  oral and  verbal apraxia    may    have commonalities  regardin  their underlying brain lesions. https://ijnl.tums.ac.ir/index.php/ijnl/article/view/618 https://ijnl.tums.ac.ir/index.php/ijnl/article/download/618/184