Prognostic value of ictal onset patterns in postsurgical outcome of temporal lobe epilepsy

  • Jafar Mehvari-Habibabadi Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Reza Basiratnia Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Houshang Moein Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mohammad Zare Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Majid Barakatain Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Yahya Aghakhani Department of Clinical Neurosciences, University of Calgary, Calgary, Canada
  • Nasim Tabrizi Isfahan University of Medical Sciences, Isfahan, Iran Department of Neurology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Keywords: Electroencephalography, Temporal Lobe, Epilepsy, Surgery, Outcome


Background: To investigate ictal onset patterns (IOP) in scalp electroencephalography (EEG) of patients with temporal lobe epilepsy (TLE) and their prognostic effect on the postoperative outcome.Methods: We conducted a retrospective cohort study between 2011 and 2015 in our referral Epilepsy Surgery Center enrolling adult patients with refractory TLE and a visible epileptogenic lesion in magnetic resonance imaging (MRI), who underwent epilepsy surgery. Demographic, clinical and MRI findings were collected and ictal findings during video-EEG monitoring were reviewed in detail. The correlation between preoperative findings and the postsurgical outcome was analyzed.Results: We reviewed 303 seizures in 93 patients. Rhythmic theta and rhythmic spike/sharp and wave were respectively the most common initial ictal pattern and late significant discharges. Engel class I outcome was observed in 88.2% of patients. Female sex, aura, the absence of secondary generalization, rhythmic theta as initial ictal pattern and concordance of ictal-interictal EEG findings were correlated with favorable 1-year postsurgical outcome.Conclusion: Preoperative clinical and EEG findings can provide valuable information regarding postsurgical prognosis in TLE patients.


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How to Cite
Mehvari-Habibabadi J, Basiratnia R, Moein H, Zare M, Barakatain M, Aghakhani Y, Tabrizi N. Prognostic value of ictal onset patterns in postsurgical outcome of temporal lobe epilepsy. IJNL. 16(4):185-91.
Original Article(s)