A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study.

Mahnaz Talebi; Mohammad Ghertasi; Aliakbar Taheraghdam; Sasan Andalib; Ehsan Sharifipour

Mahnaz Talebi Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Ghertasi Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Aliakbar Taheraghdam Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Sasan Andalib Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Ehsan Sharifipour Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Keywords: Gender, Ischemic Stroke, Risk Factor

Abstract

Background: Gender difference has been   reported in stroke risk factors and disease history. The aim of this study was to compare risk factors and the severity of ischemic stroke based upon modified Rankin Scale (mRS) and hospital mortality between two genders.
Methods: In a cross-sectional study, 341 patients (44% males and 56% females with a mean age of 68.94 ± 12.74 years) with ischemic stroke, who were hospitalized in the neurology   wards of two referral university hospital of North-West Iran (Imam Reza and Razi Hospitals), from the beginning to the end of 2011 were selected and assessed. Gender difference in terms of demographic findings, vascular risk factors, 7th   day mRS, and hospital mortality (during admission) were evaluated.
Results: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability). No significant difference in ischemic stroke severity   based   on   mRS   was   observed   between two genders. ere was a significant difference in the rate of hypertension (females = 72.3%, males = 59.3%, P = 0.010), diabetes   (females = 28.8%, males = 18.7%, P = 0.030), smoking (females = 6.3%, males = 35.3%, P < 0.001). No significant   difference   was   seen   in other   risk factors between two genders. There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).
Conclusion:The   evidence   from   the   present   study suggests that despite the existence of some difference between risk-factors in two genders, there was no difference in terms of ischemic stroke severity and mortality rate between two genders.

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